Hebei Kunsui Technology Co., Ltd.

Organic Intermediate, Pharmaceutical Intermediate
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Hebei Kunsui Technology Co., Ltd.
Country:  China (Mainland)
Business Type:  Trading Company
Mr.gui
Tel: +8613383105603
Mr.John John
Tel: 13373203779
Ms.alice
Tel: 13373203779
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URL:  http://
City:  Shijiazhuang
Street:  Shijiazhuang City, Hebei Province
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Piracetam powder 7491-74-9 CAS

Piracetam powder 7491-74-9 CAS CAS NO.7491-74-9

  • FOB Price: USD: 100.00-150.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    A(1-10)KilogramA(10-100)Kilogram

  • Product Details

Keywords

  • 7491-74-9
  • Piracetam oxiracetam impurity V
  • 2-(2-Oxopyrrolidin-1-yl)acetamide

Quick Details

  • ProName: Piracetam powder 7491-74-9 CAS
  • CasNo: 7491-74-9
  • Molecular Formula: C6H10N2O2
  • Appearance: Powder
  • Application: t is used for the treatment of memory ...
  • DeliveryTime: 3 days
  • PackAge: As request
  • Port: Shanghai
  • ProductionCapacity: 1000 Metric Ton/Year
  • Purity: 99.9%
  • Storage: Cool and dry
  • Transportation: As product request.
  • LimitNum: 1 Kilogram
  • Related Substances: Related Impurities≤0.1%
  • Residue on Ignition: 0.05%
  • Heavy Metal: <10ppm
  • Valid Period: 24 months
  • Grade: Industrial Grade,Pharma Grade,Electron...
  • Boiling Point: 408.3 °C at 760 mmHg
  • Melting Point: 151-152 °C
  • Molecular Weigh: 142.158
  • Density: 1.239

Superiority

1. A strong scientific research team .
2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products).
3. Rich export experience (with practical experience in exporting to more than 30 countries such as North America, Europe, Middle East, and Southeast Asia).
4. Professional pre-sales and after-sales services (customer first is the core belief of our sales team).
5. Ability to provide value-added services (we can provide a wealth of product solutions to help customers improve competitiveness and production.

6. Safe and fast delivery Most products have a large inventory, so the products can be sent fast after confirming payment, and the tracking number and packaging details will be notified as soon as possible; Large amount of our products are exported to many countries, such as Germany, Brazil, the United States, Spain, the United Kingdom, France, Canada, Mexico, Poland, Russia, Australia, Norway, Finland and so on, with more than 1000 kg per month. We have cooperative agents in these countries. Our customs clearance company will clear your package without customs problems.
7. Rich experience
We are a professional manufacturer of pharmaceutical chemical raw materials. We have focused on this field for many years, and our product is BP / USP / EP / enterprise standard. We guarantee all purity > 99%. High purity and good quality are one of the greatest secrets of our success; You can get the best quality and service from us

Details

 

Product name Piracetam
CAS number 7491-74-9
Purity 99%

Usages: 

Central nervous stimulant piracetam, also known as brain rehabilitation, pyriacetamide, acetamidopyrrole cycloketone, is a brain metabolism improvement drug, belongs to the cyclic derivatives of γ-aminobutyric acid, strong selectivity for central action, limited to the improvement of brain function (memory, consciousness, etc.), psychoexcitatory effect is weak, no side effects of psychotropic drugs, no dependence. It can prevent or protect the retrograde amnesia caused by hypoxia in animals, and also significantly antagonize the inhibitory effect of barbiturate salt on the central, can promote the metabolism of brain cells, increase the absorption and utilization of amino acids, proteins and glucose in the brain, have the effect of activating, protecting and repairing brain nerve cells, can promote the conversion of ADP into ATP in the brain, and improve the metabolic energy supply in the brain. It affects the excitation transmission of cholinergic neurons and promotes the synthesis of acetylcholine. Piracetam can resist the damage of brain function caused by physical and chemical factors and improve learning, memory and recall. It can improve retrograde amnesia caused by hypoxia. It is easy to absorb orally, the blood concentration reaches the peak after 30 to 40 minutes, the protein binding rate is 30%, the clearance half-life is 4 to 6 hours, and it is easy to penetrate the blood-brain barrier and reach the brain and cerebrospinal fluid. After oral administration, it cannot be broken down by the liver and excreted in its original form from the urine and stool. It is mainly used for memory and thinking disorders caused by brain diseases, organic dementia and mental retardation in children, and has a certain effect on mild and moderate senile dementia, but it is ineffective for severe patients. It is also effective in improving the symptoms of functional brain decline syndrome. Piracetam can also be used to restore consciousness in cases of encephalitis, carbon monoxide, pesticides, and alcoholism by intravenous or drip. Pharmacology and toxicology piracetam is a derivative of gamma-aminobutyric acid, which promotes thinking and memory, can directly act on the cerebral cortex, enhance protein synthesis, protect nerve cells, promote information transmission, improve learning and memory ability, improve brain injury or degeneration caused by various reasons, and improve brain function. Animal experiments have confirmed that this product can improve learning ability, fight against hypoxic memory disorders, improve the utilization of glucose and energy storage in the brain, and improve brain function. It has some effect on cognition and orientation of mild and moderate senile dementia, but has no obvious effect on severe dementia. It also has therapeutic effect on functional brain decline syndrome, such as dull response, consciousness disorder and other symptoms, so that it has been improved to a certain extent. It is effective for brain dysfunction caused by external injury, stroke and carbon monoxide poisoning. It can also be used to improve the intelligence of mentally retarded children and the treatment of nocturia. The central selection effect of this product is strong, limited to the improvement of memory and consciousness function, without the side effects of psychoactive drugs, and no dependence. Acute toxicological tests in animal experiments showed that no death was observed in mice with an intragastric dose greater than 10g/kg. The LD50 of intravenous administration was 9.2g/kg, and subacute and chronic toxicological tests did not show any adverse effects on the growth and development of rats and dogs. It has no adverse effects on the blood, heart, liver, kidney, brain and other important internal organs and functions. This information has been edited by Xiao Nan of ChemicalBook. Pharmacokinetics This product is quickly absorbed from the digestive tract after oral administration, enters the blood Chemicalbook, and crosses the blood-brain barrier to reach the brain and cerebrospinal fluid, with higher concentrations in the cerebral cortex and olfactory bulb than in the brain stem. This product easily passes the placental barrier. After oral administration, the blood concentration reaches the peak in 30-45 minutes, the plasma protein binding rate is 30%, the half-life t1/2 is 5 to 6 hours, and the apparent volume of distribution (Vd) is 0.6L/kg. Piracetam cannot be broken down by the liver when taken orally and is excreted in prototype form from urine and stool. The renal clearance rate was 86ml/min. Stool output is about 1% to 2%. Indications are mainly used for memory and thinking disorders caused by brain diseases, organic dementia and mental retardation in children, and have a certain effect on mild and moderate senile dementia, but have no effect on severe patients. It is also effective in improving the symptoms of functional brain decline syndrome. When it is used for brain injury drug poisoning, it can be used for intravenous injection or instillation. Administration and dosage Oral: 800 ~ 1600mg each time, 3 times a day, 3 to 6 weeks for a course of treatment, children dosage halved. Muscle note: 1g each time, 2-3 times a day. Static note: 4g per time, once a day. Intravenous drip: 4 ~ 8g, once a day. Dilute to 250ml with 5% glucose injection or 0.9% sodium chloride injection. Use half for the elderly and children. Adverse reactions Common gastrointestinal adverse reactions include nausea, abdominal discomfort, poor appetite, abdominal distension, abdominal pain, etc. The severity of the symptoms is directly related to the dosage. The adverse reactions of the central nervous system include excitement, irritability, dizziness, headache, insomnia, etc., but the symptoms are mild and have nothing to do with the dosage. The above symptoms disappear after withdrawal of the drug. Occasionally, mild liver function impairment, characterized by a mild elevation of aminotransferase, was observed, but was independent of drug dose. Drug interaction When combined with warfarin, prothrombin time can be prolonged and inhibition of platelet aggregation can be induced. In patients receiving anticoagulant therapy, special attention should be paid to the coagulation time when simultaneously applying piracetam to prevent the risk of bleeding, and the drug dose and usage of anticoagulant therapy should be adjusted. Precautions 1. This product easily passes the blood-brain barrier and placental barrier. It is not degraded in the body and is not transformed, and is excreted directly by the kidney, so pregnant women, newborns, hepatic and renal dysfunction are prohibited. 2. Individual patients have dry mouth, loss of appetite, urticaria and memory and thinking decline. 3. Patients with extrapyramidal diseases and Huntington's disease should not use this product to avoid aggravating symptoms. Chemical properties White crystalline powder. Melting point 151.5-152.5℃. Soluble in water, slightly soluble in ethanol, almost insoluble in ether. Odorless, slightly bitter taste. The early use of wood forest in anti-vertigo and anti-emetic medicine, as a nervous system drug, can promote and enhance the brain B function, effective for senile memory loss. It also has some effect on memory and thinking disorders caused by senile dementia and brain trauma. Use for the treatment of memory and thinking function decline caused by cerebral arteriosclerosis and cerebrovascular accidents in medicine for cooling oil, painkillers, etc., also used in the production of toothpaste, dental powder, candy, drinks, spices Production method 2-pyrrolidone as the starting material, toluene and sodium methanol salt, with ethyl chloroacetate condensation and then ammonia preparation.

About Us:

Hebei Kunsui Technology Co., Ltd. specializes in exporting high quality Pharmaceutical raw materials, plant extract, pesticide raw materials  and Chemical raw materials.
Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meet the requirements of security and environmental protection. We earned customer trust and created a good reputation during these years.

Packing & Shipping:

Packing&Delivery:
Packing and Storage: Packed in double plastic bags inside, outside with 25kg Fiber Drum.
Drum Size: 40cm*40cm*50mm, 25KG/drum Nt.;27.5Kg/drum.Gt. Store in a well-closed container away from moisture.
Shelf Life: 2 years if sealed and store away from direct sun light.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.
Delivery time: Around 3 workdays after your payment.
Payments:We accept BTC//USDT/Bank transfer.

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 
  2. Shipping details & shipping documents will be provided and sent by email. 
  3. We keep tracking the shippment until clients well received. 
  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

FAQ:

Q: Is there a discount.

Yes, for larger quantity, we always support with better price.

Q2: Can I have free samples

Yes, we can supply the free 10-20g sample except high value products, but the shipping cost be paid by you. Generally USD45 for sample fee.

Q3: How do I pay the sample fee

Paypal,,T/T or just provide your courier's account number, we prefer FEDEX.

Q4: How do you treat quality complaint

If quality problem caused by us after Third Party Test, we will send you free goods for replacement or refund your payment.

Q5:What's your MOQ and lead time

Generally MOQ is 1kg, some low value products, MOQ is 25kg and lead time is within 4-5 workdays upon your payment.

Q6: Which products you can export

We are mainly exporting herbal extracts, amino acids, vitamins, cosmetics and APIs.

Q7: Which documents you can provide

Usually, we provide Commercial Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your
markets have any special requirements, let us know.

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