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China (Mainland)
Nootropic CAS 1146963-51-0 99% J-147 Powder CAS NO.1146963-51-0
- FOB Price: USD: 150.00-180.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
A(1-10)KilogramA(10-100)Kilogram
- Product Details
Keywords
- 1146963-51-0
- J 147
- J147-API
Quick Details
- ProName: Nootropic CAS 1146963-51-0 99% J-147 P...
- CasNo: 1146963-51-0
- Molecular Formula: C18H17F3N2O2
- Appearance: Powder
- Application: Main use: puzzle
- DeliveryTime: 3 days
- PackAge: As request
- Port: Shanghai
- ProductionCapacity: 1000 Metric Ton/Year
- Purity: 99.9%
- Storage: Cool and dry
- Transportation: As product request.
- LimitNum: 1 Kilogram
- Related Substances: Related Impurities≤0.1%
- Residue on Ignition: 0.05%
- Heavy Metal: <10ppm
- Valid Period: 24 months
- Grade: Industrial Grade,Pharma Grade,Electron...
- Boiling Point: 412.8±55.0 °C(Predicted)
- Melting Point: A/N
- Molecular Weigh: 350.341
- Density: 1.18±0.1 g/cm3(Predicted)
Superiority
1. A strong scientific research team .
2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products).
3. Rich export experience (with practical experience in exporting to more than 30 countries such as North America, Europe, Middle East, and Southeast Asia).
4. Professional pre-sales and after-sales services (customer first is the core belief of our sales team).
5. Ability to provide value-added services (we can provide a wealth of product solutions to help customers improve competitiveness and production.
6. Safe and fast delivery Most products have a large inventory, so the products can be sent fast after confirming payment, and the tracking number and packaging details will be notified as soon as possible; Large amount of our products are exported to many countries, such as Germany, Brazil, the United States, Spain, the United Kingdom, France, Canada, Mexico, Poland, Russia, Australia, Norway, Finland and so on, with more than 1000 kg per month. We have cooperative agents in these countries. Our customs clearance company will clear your package without customs problems.
7. Rich experience
We are a professional manufacturer of pharmaceutical chemical raw materials. We have focused on this field for many years, and our product is BP / USP / EP / enterprise standard. We guarantee all purity > 99%. High purity and good quality are one of the greatest secrets of our success; You can get the best quality and service from us
Details
| Product name | J 147 |
| CAS number | 1146963-51-0 |
| Purity | 99% |
Usages:
Biological activity
J-147 is a particularly potent, orally active neuroprotectant that enhances cognitive function. J-147 can cross the blood-brain barrier (BBB). J-147 inhibits monoamine oxidase B (MAO B) and dopamine transporter with EC50 of 1.88 μM and 0.649 μM, respectively. J-147 has the potential to be used in Alzheimer's disease (AD) research.
MAO B; Dopamine transporter
J-147 promotes HT22 and primary cell survival in a dose-dependent manner (EC 50 value range of 0.06-0.115 μM) .
J-147 (diet is prepared by the addition of J-147 at 200ppm; 6 months) enhances memory and dendritic spine number in old mice.
The half life (t 1/2 ) of J-147 is calculated at 1.5 hrs in plasma and 2.5 hrs in brain ( per oral (PO) administration at a single dose of 20 mg/kg).
| Animal Model: | 24 male C57Bl/6 mice aged 24 months; using 8 month-old mice as controls |
| Dosage: | 200 ppm |
| Administration: | The diet was prepared by the addition of 200ppm; 6 months |
| Result: | While both young and old animals recognized when an object was moved a large distance (135 degrees), a reduction in the recognition index (RI) in aged mice was observed when the object was moved a smaller distance of 45 degrees. The reduction in the RI was reversed upon treatment with J147. |
About Us:
Hebei Kunsui Technology Co., Ltd. specializes in exporting high quality Pharmaceutical raw materials, plant extract, pesticide raw materials and Chemical raw materials.
Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meet the requirements of security and environmental protection. We earned customer trust and created a good reputation during these years.
Packing & Shipping:
Packing&Delivery:
Packing and Storage: Packed in double plastic bags inside, outside with 25kg Fiber Drum.
Drum Size: 40cm*40cm*50mm, 25KG/drum Nt.;27.5Kg/drum.Gt. Store in a well-closed container away from moisture.
Shelf Life: 2 years if sealed and store away from direct sun light.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.
Delivery time: Around 3 workdays after your payment.
Payments:We accept BTC//USDT/Bank transfer.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
FAQ:
Q: Is there a discount.
Yes, for larger quantity, we always support with better price.
Q2: Can I have free samples
Yes, we can supply the free 10-20g sample except high value products, but the shipping cost be paid by you. Generally USD45 for sample fee.
Q3: How do I pay the sample fee
Paypal,,T/T or just provide your courier's account number, we prefer FEDEX.
Q4: How do you treat quality complaint
If quality problem caused by us after Third Party Test, we will send you free goods for replacement or refund your payment.
Q5:What's your MOQ and lead time
Generally MOQ is 1kg, some low value products, MOQ is 25kg and lead time is within 4-5 workdays upon your payment.
Q6: Which products you can export
We are mainly exporting herbal extracts, amino acids, vitamins, cosmetics and APIs.
Q7: Which documents you can provide
Usually, we provide Commercial Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your
markets have any special requirements, let us know.